Prof. dr. R. Rissman
Functie:
CHDR/LACDR
Expertise on healthy and diseased skin in clinical testing
Expertises
- Phase1, first-in-human studies (topical and systemic)
- Proof-of-concept studies in various skin diseases
- Multimodal assessment of drug effects (biophysical, molecular, cellular, patient-reported outcomes)
- Multi-center recruitment
- Design and execution of clinical pharmacology studies, PK-PD
- Translational science, experimental dermatology
Main used techniques
- Imaging, microbiome, biophysical methods, multi-omics
- Biometry, planimetry
- Transcriptomics, proteomics
- Lipidomics
- Remote monitoring of patients
- Clinical assessments (dermatologists)
- Skin challenge models (acute inflammatory, itch, delayed-type hypersensitivity, wound healing)